Description
BMI1 Polyclonal Antibody | E-AB-40381 | Gentaur US, UK & Europe Disrtribition
Reactivity: Mouse
Host: Rabbit
Isotype: IgG
Application: WB
Research Area: Cell Biology, Epigenetics and Nuclear Signaling, Stem Cells, Cancer
Background: BMI- 1 is one of polycomb group genes, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16Ink4a and p19Arf genes and is required for maintenance of adult hematopoietic and neural stem cells. The antibody reacts with the 37kd BMI1 protein.
Lead Time: 7~10 days
Concentration: 0.18 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Mouse Polycomb complex protein BMI-1 protein
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3
Purification: Antigen Affinity Purification
Dilution: WB 1:500-1:1000
Conjugation: Unconjugated
Calculated Molecular Weight: 36 kDa
Observed Molecular Weight: 36 kDa
Clonality: Polyclonal