BMI1 Polyclonal Antibody | E-AB-40381

BMI1 Polyclonal Antibody | E-AB-40381 | Gentaur US, UK & Europe Disrtribition

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Application: WB

Research Area: Cell Biology, Epigenetics and Nuclear Signaling, Stem Cells, Cancer

Background: BMI- 1 is one of polycomb group genes, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16Ink4a and p19Arf genes and is required for maintenance of adult hematopoietic and neural stem cells. The antibody reacts with the 37kd BMI1 protein.

Lead Time: 7~10 days

Concentration: 0.18 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Mouse Polycomb complex protein BMI-1 protein

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Purification: Antigen Affinity Purification

Dilution: WB 1:500-1:1000

Conjugation: Unconjugated

Calculated Molecular Weight: 36 kDa

Observed Molecular Weight: 36 kDa

Clonality: Polyclonal