Description
BMI1 Antibody | F51332-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: FACS, WB, IHC, IF, ELISA
Buffer: N/A
Limitation: This BMI1 antibody is available for research use only.
Purity: Antigen affinity
Description: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. [UniProt]
Immunogen: This BMI1 antibody was produced from rabbits immunized with BMI1 recombinant protein.
Storage: Aliquot the BMI1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
