Description
BLK, GST-tag | 40401 | Gentaur US, UK & Europe Disrtribition
Category: Kinase/Cytoplasmic Tyrosine
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Background: BLK, also known as B lymphoid kinase, is a 55 kd tyrosine kinases with a SH3, SH2 and catalytic domains that contain consensus sequences of the src protein tyrosine kinase family. BLK is expressed specifically in the B cell lineage and plays a role in signal transduction pathway that is restricted to B lymphoid cells (1). Stimulation of resting B-lymphocytes with antibodies to surface immunoglobulin (sIgD or sIgM) induces activation of BLK (2).
Description: Recombinant full-length human BLK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is BC007371.
Product Type: Protein
Shippement Condition: -80°C
