Description
Biotinylated SARS-CoV-2 Nucleocapsid protein, His, Avitag™ (BA.2*&BA.3*/Omicron) | NUN-C82E9-25ug| Gentaur Distribution US, UK & Europe
Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
Source: Biotinylated SARS-CoV-2 Nucleocapsid protein, His, Avitag (BA.2*&BA.3*/Omicron) (NUN-C82E9) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1 (P13L, ERS31-33del, R203K, G204R, S413R) ). The nucleocapsid mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2; GISAID clade: GRA; Nextstrain clade: 21L & Pango lineage: BA.3; GISAID clade: GRA; Nextstrain clade: 21M).
Format: Powder.
Tag: C-6×His & C-Avi.
Expression System: HEK293.
Expression Region: Met 1 - Ala 419.
Conjugate: Biotin-labeled.
Molecular Weight: 48.8 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 48.8 kDa. The protein migrates as 33 kDa and 50-60 kDa under reducing (R) condition (SDS-PAGE).
Purity: 90%.
Buffer: PBS, 0.2M Arginine, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
