Description
Biotinylated Rhesus macaque CD5 Protein, His, Avitag™ (MALS verified) | CD5-R82E3-25ug| Gentaur Distribution US, UK & Europe
T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1, which is phosphorylated on tyrosine residues by LYN, so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development, selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.
Source: Biotinylated Rhesus macaque CD5 Protein, His, Avitag (CD5-R82E3) is expressed from human 293 cells (HEK293). It contains AA Arg 25 - Thr 382 (Accession # F6V5Q9).
Format: Powder.
Tag: C-10×His & C-Avi.
Expression System: HEK293.
Expression Region: Arg 25 - Thr 382.
Conjugate: Biotin-labeled.
Molecular Weight: 43 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 43 kDa. The protein migrates as 52-57 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
