Biotinylated Mouse TSLP Protein, His, Avitag™ | TSP-M82E3-25ug

Biotinylated Mouse TSLP Protein, His, Avitag™ | TSP-M82E3-25ug| Gentaur Distribution US, UK & Europe

Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.

Source: Biotinylated Mouse TSLP, His, Avitag (TSP-M82E3) is expressed from human 293 cells (HEK293). It contains AA Tyr 20 - Glu 140 (Accession # Q9JIE6-1).

Format: Powder.

Tag: C-10×His & C-Avi.

Expression System: HEK293.

Expression Region: Tyr 20 - Glu 140.

Conjugate: Biotin-labeled.

Molecular Weight: 17.6 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 17.6 kDa. The protein migrates as 25-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT