Biotinylated Mouse IgG2a Fc Protein, Avitag™ (MALS verified) | IGA-M8210-25ug

Biotinylated Mouse IgG2a Fc Protein, Avitag™ (MALS verified) | IGA-M8210-25ug| Gentaur Distribution US, UK & Europe

Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F (ab) s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis.

Source: Biotinylated Mouse IgG2a Fc, Avitag (IGA-M8210) is expressed from human 293 cells (HEK293). It contains AA Glu 98 - Lys 330 (Accession # P01863).

Format: Powder.

Tag: C-Avi.

Expression System: HEK293.

Expression Region: Glu 98 - Lys 330.

Conjugate: Biotin-labeled.

Molecular Weight: 28.2 kDa.

Characteristics: This protein carries an Avi tag (Avitag™) at the C-terminus. The protein has a calculated MW of 28.2 kDa. The protein migrates as 32-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: Tris with Glycine,  Arginine and NaCl,  pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT