Description
Biotinylated Mouse Cadherin-17 / CDH17 Protein, His, Avitag™ (MALS verified) | CA7-M82E7-200ug| Gentaur Distribution US, UK & Europe
Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Source: Biotinylated Mouse Cadherin-17 Protein, His, Avitag (CA7-M82E7) is expressed from human 293 cells (HEK293). It contains AA Phe 26 - Met 786 (Accession # Q9R100-1).
Format: Powder.
Tag: C-10×His & C-Avi.
Expression System: HEK293.
Expression Region: Phe 26 - Met 786.
Conjugate: Biotin-labeled.
Molecular Weight: 87.9 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 87.9 kDa. The protein migrates as 110-116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: 20 mM Tris, 150 mM NaCl, pH8.0.
Storage Conditions: -20℃.
Shipping Conditions: RT
