Biotinylated Human PTK7 / CCK4 protein, Fc, Avitag™ (MALS verified) | PT7-H82F5-200ug

Biotinylated Human PTK7 / CCK4 protein, Fc, Avitag™ (MALS verified) | PT7-H82F5-200ug| Gentaur Distribution US, UK & Europe

PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.

Source: Biotinylated Human PTK7 protein, Fc, Avitag (PT7-H82F5) is expressed from human 293 cells (HEK293). It contains AA Ala 31 - Thr 704 (Accession # Q13308-1).

Format: Powder.

Tag: C-Fc & C-Avi.

Expression System: HEK293.

Expression Region: Ala 31 - Thr 704.

Conjugate: Biotin-labeled.

Molecular Weight: 102.8 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 102.8 kDa. The protein migrates as 125-145 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT