Biotinylated Human PD-L2 / B7-DC Protein, Avitag™, His Tag (recommended for biopanning) | PD2-H82E8-200ug

Biotinylated Human PD-L2 / B7-DC Protein, Avitag™, His Tag (recommended for biopanning) | PD2-H82E8-200ug| Gentaur Distribution US, UK & Europe

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Source: Biotinylated Human PD-L2, Avitag, His Tag (recommended for biopanning) (PD2-H82E8) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Pro 219 (Accession # AAI13679).

Format: Powder.

Tag: C-Avi & C-6×His.

Expression System: HEK293.

Expression Region: Leu 20 - Pro 219.

Conjugate: Biotin-labeled.

Molecular Weight: 25.2 kDa.

Characteristics: This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 25.2 kDa. The protein migrates as 33-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT