Description
Biotinylated Human MICA Protein, Fc, Avitag™ (MALS verified) | MIA-H82F6-200ug| Gentaur Distribution US, UK & Europe
MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.
Source: Biotinylated Human MICA Protein, Fc, Avitag (MIA-H82F6) is expressed from human 293 cells (HEK293). It contains AA Glu 24 - Gln 308 (Accession # Q29983-1).
Format: Powder.
Tag: C-Fc & C-Avi.
Expression System: HEK293.
Expression Region: Glu 24 - Gln 308.
Conjugate: Biotin-labeled.
Molecular Weight: 61.0 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 61.0 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
