Description
Biotinylated Human LAG-3 / CD223 Protein, Mouse IgG2a Fc, Avitag™ (MALS verified) | LA3-H82F3-25ug| Gentaur Distribution US, UK & Europe
Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
Source: Biotinylated Human LAG-3, Mouse IgG2a Fc, Avitag (LA3-H82F3) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Leu 450 (Accession # P18627-1).
Format: Powder.
Tag: C-mFc (mIgG2a) & C-Avi.
Expression System: HEK293.
Expression Region: Leu 23 - Leu 450.
Conjugate: Biotin-labeled.
Molecular Weight: 75.4 kDa.
Characteristics: This protein carries a mouse IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 75.4 kDa. The protein migrates as 100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
