Description
Biotinylated Human Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein, His, Avitag™&Tag Free | IT1-H82Wb-25ug| Gentaur Distribution US, UK & Europe
Human Integrin alpha 8 beta 1 Heterodimer Protein consists of ITGA8 and ITGB1. The integrin alpha 8 subunit, isolated by low stringency hybridization, is a novel integrin subunit that associates with beta 1. The recently identified alpha 8 integrin subunit associates with beta 1 and is predominantly expressed in smooth muscle and other contractile cells in adult tissues, and in mesenchymal and neural cells during development. In addition, Integrin alpha 8 beta 1 is a receptor for fibronectin and can promote attachment, cell spreading, and neurite outgrowth on fibronectin.
Source: Biotinylated Human ITGA8&ITGB1 Heterodimer Protein, His, Avitag&Tag Free (IT1-H82Wb) is expressed from human 293 cells (HEK293). It contains AA Phe 39 - Leu 1012 (ITGA8) & Gln 21 - Asp 728 (ITGB1) (Accession # P53708-1 (ITGA8) & P05556-1 (ITGB1) ).
Format: Powder.
Tag: C-10×His & C-Avi | Native.
Expression System: HEK293.
Expression Region: Phe 39 - Leu 1012 (ITGA8) & Gln 21 - Asp 728 (ITGB1).
Conjugate: Biotin-labeled.
Molecular Weight: 116.4 kDa (ITGA8) & 83.7 kDa (ITGB1).
Characteristics: Biotinylated Human ITGA8&ITGB1 Heterodimer Protein, His, Avitag&Tag Free, produced by co-expression of ITGA8 and ITGB1, has a calculated MW of 116.4 kDa (ITGA8) and 83.7 kDa (ITGB1). Subunit ITGA8 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and an Avi tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The non-reducing (NR) protein migrates as 140-150 kDa (ITGA8) and 100-115 kDa (ITGB1) respectively due to glycosylation.
Purity: 90%.
Buffer: 50 mM Tris, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
