Description
Biotinylated Human HLA-A*24:02&B2M&WT-1 (CYTWNQMNL) Complex Protein (Monomer, MALS verified) | HLW-H82E6-200ug| Gentaur Distribution US, UK & Europe
Wilms tumor gene 1 (WT1) ，is an attractive target antigen for leukemia and solid cancer. WT1-specific adoptive immunotherapy has developed for tumor treatment in recent years. WT1 has been proved wildly expressed in breast, colon and ovarian cancer. It participates in cell growth, differentiation and apoptosis regulation. The human HLA-A*2402 WT-1 (CYTWNQMNL) complex protein is a complex of HLA-A*2402 of the MHC Class I, B2M and CYTWNQMNL peptide of the WT-1.
Source: Biotinylated Human HLA-A*24:02&B2M&WT-1 (CYTWNQMNL) Complex Protein (HLW-H82E6) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 305 (HLA-A*24:02) & Ile 21 - Met 119 (B2M) & CYTWNQMNL peptide (Accession # AAA59600.1 (HLA-A*24:02) & P61769 (B2M) & CYTWNQMNL).
Format: Liquid.
Tag: C-10×His & C-Avi.
Expression System: HEK293.
Expression Region: Gly 25 - Ile 305 (HLA-A*24:02) & Ile 21 - Met 119 (B2M) & CYTWNQMNL peptide.
Conjugate: Biotin-labeled.
Molecular Weight: 35.8 kDa and 11.7 kDa.
Characteristics: Biotinylated Human HLA-A*24:02&B2M&WT-1 (CYTWNQMNL) Complex Protein is produced by co-expression of HLA and B2M loaded with WT-1 peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 35.8 kDa and 11.7 kDa. The protein migrates as 39-41 kDa and 10 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -70℃.
Shipping Conditions: Dry ice
