Description
Biotinylated Human HLA-A*03:01&B2M&KRASG12C (VVGACGVGK) Complex Protein (Monomer, MALS verified) | HLC-H82E6-200ug| Gentaur Distribution US, UK & Europe
The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Biotinylated Human HLA-A*0301 KRASG12C (VVGACGVGK) complex protein is a complex of HLA-A*0301 of the MHC Class I, B2M, and VVGACGVGK peptide of the KRASG12C.
Source: Biotinylated Human HLA-A*03:01&B2M&KRASG12C (VVGACGVGK) Complex Protein (HLC-H82E6) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVGACGVGK peptide (Accession # P04439 (HLA-A*03:01) & P61769 (B2M) & VVGACGVGK).
Format: Powder.
Tag: C-10×His & C-Avi.
Expression System: HEK293.
Expression Region: Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVGACGVGK peptide.
Conjugate: Biotin-labeled.
Molecular Weight: 35.9 kDa and 11.7 kDa.
Characteristics: Biotinylated Human HLA-A*03:01&B2M&KRASG12C (VVGACGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12C peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 36.0 kDa and 11.7 kDa. The protein migrates as 40-46 kDa and 12 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
