Biotinylated Human HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Complex Protein (Monomer, MALS verified) | HLM-H82E3-200ug

Biotinylated Human HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Complex Protein (Monomer, MALS verified) | HLM-H82E3-200ug| Gentaur Distribution US, UK & Europe

The MAGE-A3 antigen is a cancer-testis antigen and is expressed intracellularly in various solid tumor tissues, MAGE-A3 112-120 peptide (KVAELVHFL) is a cytotoxic T lymphocyte (CTL) epitope presented by HLA-A*0201. The Human HLA-A*0201 MAGE-A3 (KVAELVHFL) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and KVAELVHFL peptide of the MAGE-A3.

Source: Biotinylated Human HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Complex Protein (HLM-H82E3) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & KVAELVHFL peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769-1 (B2M) & KVAELVHFL).

Format: Powder.

Tag: C-10×His & C-Avi.

Expression System: HEK293.

Expression Region: Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & KVAELVHFL peptide.

Conjugate: Biotin-labeled.

Molecular Weight: 36.3 kDa and 11.7 kDa.

Characteristics: Biotinylated Human HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Complex Protein is produced by co-expression of HLA and B2M loaded with MAGE-A3 peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 36.3 kDa and 11.7 kDa. The protein migrates as 38-44 kDa and 12 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT