Description
Biotinylated Human HLA-A*02:01&B2M&HER2 (KIFGSLAFL) Complex Protein (Monomer, MALS verified) | HL2-H82E5-200ug| Gentaur Distribution US, UK & Europe
Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2, HER-2, HER-2 /neu, NEU, NGL, TKR1 and c-erb B2, and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. The Human HLA-A*0201 HER2 (KIFGSLAFL) ) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M and KIFGSLAFL peptide of the HER2.
Source: Biotinylated Human HLA-A*02:01&B2M&HER2 (KIFGSLAFL) Complex Protein (HL2-H82E5) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & KIFGSLAFL peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769 (B2M) & KIFGSLAFL).
Format: Powder.
Tag: C-10×His & C-Avi.
Expression System: HEK293.
Expression Region: Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & KIFGSLAFL peptide.
Conjugate: Biotin-labeled.
Molecular Weight: 36.3 kDa and 11.7 kDa.
Characteristics: Biotinylated Human HLA-A*02:01&B2M&HER2 (KIFGSLAFL) Complex Protein is produced by co-expression of HLA and B2M loaded with HER2 peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 36.3 kDa and 11.7 kDa. The protein migrates as 40-43 kDa and 10 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
