Biotinylated Human FcRn / FCGRT&B2M Heterodimer Protein, His, Avitag™ (MALS & SPR verified) | FCM-H82W7-200ug

Biotinylated Human FcRn / FCGRT&B2M Heterodimer Protein, His, Avitag™ (MALS & SPR verified) | FCM-H82W7-200ug| Gentaur Distribution US, UK & Europe

FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

Source: Biotinylated Human FCGRT&B2M Heterodimer Protein, His, Avitag (FCM-H82W7) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Ser 297 (FCGRT) & Ile 21 - Met 119 (B2M) (Accession # P55899-1 (FCGRT) & P61769-1 (B2M) ).

Format: Powder.

Tag: C-10×His & C-Avi | Native.

Expression System: HEK293.

Expression Region: Ala 24 - Ser 297 (FCGRT) & Ile 21 - Met 119 (B2M).

Conjugate: Biotin-labeled.

Molecular Weight: 34.2 kDa (FCGRT) & 11.7 kDa (B2M).

Characteristics: Biotinylated Human FCGRT&B2M Heterodimer Protein, His, Avitag, produced by co-expression of FCGRT and B2M, has a calculated MW of 34.2 kDa (FCGRT) and 11.7 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) and subunit Beta-2 microglobulin (B2M) contains no tag at the C-terminus. The reducing (R) protein migrates as 38-40 kDa (FCGRT) and 12 kDa (B2M) respectively due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT