Biotinylated Human CD45 / PTPRC Protein, His, Avitag™ | CD5-H82E8-200ug

Biotinylated Human CD45 / PTPRC Protein, His, Avitag™ | CD5-H82E8-200ug| Gentaur Distribution US, UK & Europe

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

Source: Biotinylated Human CD45 / PTPRC Protein, His, Avitag (CD5-H82E8) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Lys 482 (Accession # P08575-8).

Format: Powder.

Tag: C-Fc & C-Avi.

Expression System: HEK293.

Expression Region: Gln 26 - Lys 482.

Conjugate: Biotin-labeled.

Molecular Weight: 54.9 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 54.9 kDa. The protein migrates as 120-150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT