Biotinylated Human CD4 Protein, Fc, Avitag™ (MALS verified) | CD4-H82F3-25ug

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SKU:
716-CD4-H82F3-25ug
Availability:
IN STOCK
Weight:
1.20 KGS
€520.00
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Description

Biotinylated Human CD4 Protein, Fc, Avitag™ (MALS verified) | CD4-H82F3-25ug| Gentaur Distribution US, UK & Europe

T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

Source: Biotinylated Human CD4, Fc, Avitag (CD4-H82F3) is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Pro 396 (Accession # P01730-1).

Format: Powder.

Tag: C-Fc & C-Avi.

Expression System: HEK293.

Expression Region: Lys 26 - Pro 396.

Conjugate: Biotin-labeled.

Molecular Weight: 69.7 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 69.7 kDa. The protein migrates as 80 kDa under reducing (R) condition, and 150 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: Tris with Glycine,  Arginine and NaCl,  pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT

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Additional Information

Size:
25 ug
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