Description
Biotinylated Human CD3E&CD3D Heterodimer Protein, Fc, His Tag&Fc, Flag Tag, ultra sensitivity (primary amine labeling) (MALS verified) | CDD-H82W0-25ug| Gentaur Distribution US, UK & Europe
T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Source: MABSol® Biotinylated Human CD3E&CD3D Heterodimer Protein, Fc, His Tag&Fc, Flag Tag, primary amine labeling (CDD-H82W0) is expressed from human HEK293 cells. It contains AA Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D) (Accession # NP_000724.1 (CD3E) & NP_000723.1 (CD3D) ). It is the biotinylated form of Human CD3E&CD3D Heterodimer Protein, Fc, His Tag&Fc, Flag Tag (CDD-H52W0).
Format: Powder.
Tag: C-Fc & C-6×His | C-Fc & C-Flag.
Expression System: HEK293.
Expression Region: Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D).
Conjugate: Biotin-labeled.
Molecular Weight: 39.2 kDa (CD3E), 37.5 kDa (CD3D).
Characteristics: The subunit CD3E carries a human IgG1 Fc fragment at the C-terminus, followed by a polyhistidine tag. The subunit CD3D carries a human IgG1 Fc fragment at the C-terminus, followed by a flag tag. The protein has a calculated MW of 39.2 kDa (CD3E) and 37.5 kDa (CD3D) . The protein migrates as 45-55 kDa on a SDS-PAGE gel under reducing (R) condition due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
