Biotinylated Human CD39 (R138A, M139A, E142K) Protein, His, Avitag™ (active enzyme) | CD9-H82E8-25ug

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SKU:
716-CD9-H82E8-25ug
Availability:
IN STOCK
Weight:
1.20 KGS
€520.00
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Description

Biotinylated Human CD39 (R138A, M139A, E142K) Protein, His, Avitag™ (active enzyme) | CD9-H82E8-25ug| Gentaur Distribution US, UK & Europe

CD39 is also known as Ectonucleoside triphosphate diphosphohydrolase 1, ENTPD1, NTPDase 1, Ecto-ATPDase 1, in the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. NTPDase-1 was originally described as CD39, a B lymphocyte cell surface marker, but it is also present on the surface of natural killer cells, T cells, and some endothelial cells.Regulatory T cells (Tregs) mediate immunosuppression through multiple, non-redundant, cell-contact dependent and independent mechanisms, a growing body of evidence suggests an important role for the CD39-CD73-adenosine pathway. CD39 ectonucleotidase is the rate-limiting enzyme of a cascade leading to the generation of suppressive adenosine that alters CD4 and CD8 T cell and natural killer cell antitumor activities.

Source: Biotinylated Human CD39 (R138A, M139A, E142K) Protein, His, Avitag (CD9-H82E8) is expressed from human 293 cells (HEK293). It contains AA Thr 38 - Val 478 (Accession # P49961-1 (R138A, M139A, E142K) ).

Format: Powder.

Tag: C-10×His & C-Avi.

Expression System: HEK293.

Expression Region: Thr 38 - Val 478.

Conjugate: Biotin-labeled.

Molecular Weight: 53.9 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 53.9 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 20 mM Tris, 150 mM NaCl, pH8.0.

Storage Conditions: -20℃.

Shipping Conditions: RT

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Additional Information

Size:
25 ug
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