Description
Biotinylated Human CD3 epsilon&CD3 delta Heterodimer Protein, His, Avitag™&Tag Free (MALS verified) | CDD-H82W6-25ug| Gentaur Distribution US, UK & Europe
T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Source: Biotinylated Human CD3E&CD3D Heterodimer Protein, His, Avitag&Tag Free (CDD-H82W6) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D) (Accession # P07766-1 (CD3E) & P04234-1 (CD3D) ).
Format: Powder.
Tag: C-10×His & C-Avi | Native.
Expression System: HEK293.
Expression Region: Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D).
Conjugate: Biotin-labeled.
Molecular Weight: 18.6 kDa (CD3E) and 13.4 kDa (CD3D).
Characteristics: Biotinylated Human CD3E&CD3D Heterodimer Protein, His, Avitag&Tag Free is produced by co-expression of CD3E and CD3D, has a calculated MW of 18.6 kDa (CD3E) and 13.4 kDa (CD3D). Subunit CD3E is fused with a polyhistidine tag and an Avi tag (Avitag™) at the C-terminus and subunit CD3D contains no tag. As a result of glycosylation, the heterodimer protein migrates as 20-28 kDa under reducing (R) condition, and 38-47 kDa under non-reducing (NR) condition (SDS-PAGE).
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
