Description
Biotinylated Human CD3 epsilon&CD3 delta Heterodimer Protein, Fc, His, Avitag™&Fc, Flag, Avitag™ (MALS verified) | CDD-H82F6-200ug| Gentaur Distribution US, UK & Europe
T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Source: MABSol® Biotinylated Human CD3E&CD3D Heterodimer Protein, Fc, His, Avitag&Fc, Flag, Avitag (CDD-H82F6) is expressed from human HEK293 cells. It contains AA Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D) (Accession # P07766-1 (CD3E) & P04234-1 (CD3D) ). It is the biotinylated form of Human CD3 epsilon & CD3 delta Protein.
Format: Powder.
Tag: C-Fc & C-10×His & C-Avi | C-Fc & C-Flag & C-Avi.
Expression System: HEK293.
Expression Region: Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D).
Conjugate: Biotin-labeled.
Molecular Weight: 45.1 kDa (CD3E) & 42.6 kDa (CD3D).
Characteristics: Biotinylated Human CD3E&CD3D Heterodimer Protein, Fc, His, Avitag&Fc, Flag, Avitag is produced by co-expression of CD3E and CD3D, has a calculated MW of 45.1 kDa (CD3E) & 42.6 kDa (CD3D). Subunit CD3E is fused with a human IgG1 Fc fragment at the C-terminus, followed by an Avi tag (Avitag™), the polyhistidine tag is inserted in-between the Fc and Avi tags at the C-terminus and subunit CD3D contains a human IgG1 Fc fragment at the C-terminus, followed by an Avi tag (Avitag™), the flag tag is inserted in-between the Fc and Avi tags at the C-terminus. As a result of glycosylation, the heterodimer protein migrates as 50-60 kDa under reducing (R) condition.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
