Description
Biotinylated Human CA125 / MUC16 Protein, Fc, Avitag™ | CA5-H82F4-200ug| Gentaur Distribution US, UK & Europe
The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.
Source: Biotinylated Human CA125, Fc, Avitag (CA5-H82F4) is expressed from human 293 cells (HEK293). It contains AA Gly 12660 - Met 12923 (Accession # Q8WXI7-1).
Format: Powder.
Tag: C-Fc & C-Avi.
Expression System: HEK293.
Expression Region: Gly 12660 - Met 12923.
Conjugate: Biotin-labeled.
Molecular Weight: 56.9 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 56.9 kDa. The protein migrates as 75-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
