Biotinylated Human BTN2A1 Protein, Fc, Avitag™ (MALS verified) | BT1-H52F5-25ug

Biotinylated Human BTN2A1 Protein, Fc, Avitag™ (MALS verified) | BT1-H52F5-25ug| Gentaur Distribution US, UK & Europe

Duplication events have led to three paralogues of BTN2A in primates: BTN2A1, BTN2A2, and BTN2A3. In humans, only BTN2A1 has been functionally characterised; it has been detected on epithelial cells and leukocytes, and identified as a novel ligand of dendritic cell-specific ICAM-3 grabbing nonintegrin (DCSIGN), a C-type lectin receptor that acts as an internalization receptor for HIV-1, HCV, and other pathogens. BTN2A2 mRNA has been shown to be expressed in circulating human immune cells.

Source: Biotinylated Human BTN2A1, Fc, Avitag (BT1-H52F5) is expressed from human 293 cells (HEK293). It contains AA Gln 29 - Ala 248 (Accession # Q7KYR7-2).

Format: Powder.

Tag: C-Fc & C-Avi.

Expression System: HEK293.

Expression Region: Gln 29 - Ala 248.

Conjugate: Biotin-labeled.

Molecular Weight: 52.7 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 52.7 kDa. The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT