Description
Biotinylated Human BLAME / SLAMF8 Protein, His, Avitag™ | BLE-H82E4-200ug| Gentaur Distribution US, UK & Europe
BLAME (B-lymphocyte activator macrophage expressed) is also known as SLAM family member 8 (SLAMF8), CD353. BLAME is a cell surface receptor that is expressed upon activation of macrophages (MΦs) by IFN-γ or bacteria, is a negative regulator of ROS in response to Gram+ and Gram- bacteria. May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor. SLAMF8 is a costimulatory molecule that affects the activation of macrophages in inflammation and in immunosuppression and inflammation response to glioma cells could aid immunotherapy for glioma.
Source: Biotinylated Human BLAME, His, Avitag (BLE-H82E4) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Asp 233 (Accession # Q9P0V8-1).
Format: Powder.
Tag: C-10×His & C-Avi.
Expression System: HEK293.
Expression Region: Ala 23 - Asp 233.
Conjugate: Biotin-labeled.
Molecular Weight: 27.1 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 27.1 kDa. The protein migrates as 30-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 85%.
Buffer: 50 mM Sodium Citrate, 150 mM NaCl, pH5.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
