Description
Biotinylated Human 4-1BB Ligand / TNFSF9 (71-254) Protein, Fc, Avitag™, premium grade | 41L-H82Fa-25ug| Gentaur Distribution US, UK & Europe
Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
Source: Biotinylated Human 4-1BB (71-254) Ligand, Fc, Avitag, premium grade (41L-H82Fa) is expressed from human 293 cells (HEK293). It contains AA Arg 71 - Glu 254 (Accession # P41273-1).
Format: Powder.
Tag: N-Avi & N-Fc.
Expression System: HEK293.
Expression Region: Arg 71 - Glu 254.
Conjugate: Biotin-labeled.
Molecular Weight: 89.2 kDa.
Characteristics: This protein carries an Avi tag (Avitag™) at the N-terminus, followed by a human IgG1 Fc tag. The protein has a calculated MW of 89.2 kDa. The protein migrates as 90-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT