Description
Biotinylated Cynomolgus NKG2A&CD94 Protein, Fc, Avitag™ (MALS verified) | NC4-C82F7-25ug| Gentaur Distribution US, UK & Europe
CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA) -E on target cells.
Source: Biotinylated Cynomolgus NKG2A&CD94, Fc, Avitag (NC4-C82F7) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94) (Accession # Q68VD2 (NKG2A) & Q68VD4 (CD94) ).
Format: Powder.
Tag: C-Fc & C-Avi.
Expression System: HEK293.
Expression Region: Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94).
Conjugate: Biotin-labeled.
Molecular Weight: 56.8 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 56.8 kDa. The protein migrates as 65-68 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
