Description
Biotinylated Cynomolgus CD3E&CD3D Heterodimer Protein, His, Avitag™&Tag Free (MALS verified) | CDD-C82W6-200ug| Gentaur Distribution US, UK & Europe
T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Source: Biotinylated Cynomolgus CD3E&CD3D Heterodimer Protein, His, Avitag&Tag Free (CDD-C82W6) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Asp 117 (CD3E) & Phe 22 - Ala 105 (CD3D) (Accession # Q95LI5-1 (CD3E) & Q95LI8-1 (CD3D) ).
Format: Powder.
Tag: C-10×His & C-Avi | Native.
Expression System: HEK293.
Expression Region: Gln 22 - Asp 117 (CD3E) & Phe 22 - Ala 105 (CD3D).
Conjugate: Biotin-labeled.
Molecular Weight: 17.8 kDa (CD3E) & 13.5 kDa (CD3D).
Characteristics: Biotinylated Cynomolgus CD3E&CD3D Heterodimer Protein, His, Avitag&Tag Free is produced by co-expression of CD3E and CD3D, has a calculated MW of 17.8 kDa (CD3E) and 13.5 kDa (CD3D). Subunit CD3E is fused with a polyhistidine tag and followed by an Avi tag (Avitag™) and subunit CD3D contains no tag at the C-terminus. The reducing (R) heterodimer protein migrates as 21-23 kDa (CD3E) and 19-21 kDa (CD3D) due to glyosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
