Biotinylated Canine FcRn / FCGRT&B2M Heterodimer Protein, His, Avitag™&Tag Free (MALS & SPR verified) | FCM-C82W9-200ug

Biotinylated Canine FcRn / FCGRT&B2M Heterodimer Protein, His, Avitag™&Tag Free (MALS & SPR verified) | FCM-C82W9-200ug| Gentaur Distribution US, UK & Europe

FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

Source: Biotinylated Canine FCGRT&B2M Heterodimer Protein, His, Avitag&Tag Free (FCM-C82W9) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Pro 298 & Val 28 - Asn 125 (Accession # XP_038512242.1 & NP_001271408.1).

Format: Powder.

Tag: C-10×His & C-Avi | Native.

Expression System: HEK293.

Expression Region: Ala 23 - Pro 298 & Val 28 - Asn 125.

Conjugate: Biotin-labeled.

Molecular Weight: 28.3 kDa | 11.5 kDa.

Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 28.3 kDa | 11.5 kDa. The protein migrates as ＜14.4 kDa and 38-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT