Description
Biotinylated Anti-Human CD28 Antibody, Mouse IgG1, Avitag™, premium grade | CD8-BM225-25ug| Gentaur Distribution US, UK & Europe
T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2) . When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs) . The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
Source: Biotinylated AntiN/AHuman CD28 Antibody, Mouse IgG1, Avitag, premium grade is a chimeric monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which combines the variable region of a mouse monoclonal antibody. The mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and BN/Alymphocytes obtained from a mouse immunized with CD28.
Molecule: CD28.
Species: Mouse.
Tag: Mouse IgG1 & Avi | Mouse Kappa.
Conjugate: Biotin-labeled.
Purity: 95%.
Charactirization: PBS, pH7.4.
Storage Conditions: -70℃.
Shipping Conditions: Dry ice
