BEX3 Antibody / NGFRAP1 / NADE | RQ6827

BEX3 Antibody / NGFRAP1 / NADE | RQ6827 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: WB, FACS, Direct ELISA

Buffer: Lyophilized from 1X PBS with 2% Trehalose

Limitation: This BEX3 antibody is available for research use only.

Purity: Antigen affinity purified

Description: Protein BEX3 is a protein that in humans is encoded by the BEX3 gene. BEX3 (brain-expressed X-linked protein 3), also called NGFRAP1 (nerve growth factor receptor associated protein 1), NADE (p75NTR-associated death executor) or FAP-1 (Fas-associated phosphatase-1), is a 24 kDa member of the BEX protein family. A nuclear export signal (aa 77-87) allows NGFRAP1 to export bound p75NTR. It is widely expressed, but highest in ovarian granulosa cells, testis, prostate, seminal vesicle and liver. Except for a 13-19 amino acid (aa) rodent Arg/His region at aa 35 that is not found in humans, human NGFRAP1 shares 94% aa identity with mouse and rat NGFRAP1. In humans, a 101 aa isoform with an alternative start site at aa 11 has been described.

Immunogen: Recombinant human protein (amino acids Q39-H103) was used as the immunogen for the BEX3 antibody.

Storage: After reconstitution, the BEX3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.