Beta Tubulin Antibody / TUBB3 | V8309SAF-100UG

Beta Tubulin Antibody / TUBB3 | V8309SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: TBBT3-1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P, WB

Buffer: N/A

Limitation: This Beta Tubulin antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance. Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion. Plays a role in dorsal root ganglion axon projection towards the spinal cord. [UniProt]

Immunogen: Amino acids 437-450 were used as the immunogen for the Beta Tubulin antibody.

Storage: Store the Beta Tubulin antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).