Description
BET Bromodomain Ligand | 33000 | Gentaur US, UK & Europe Disrtribition
Category: Bromodomain/Ligands
Application: Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling. It is a component of several BPS Bioscience BRD Assay Kits.
Background: Bromodomains function as acetyl-lysine binding domains, and bromodomain/ acetyl-lysine recognition can regulate histone modification, DNA replications, chromatin remodeling, and gene transcription.
Description: The BET Bromodomain Ligand is peptide histone H4 (1-21), acetylated at lysine 5, 8, 12 and 16. It contains a C-terminal GG linker, followed by a biotinylated Lys. This peptide is suitable for use as a ligand for several bromodomains including members of the BET bromodomain family: BRD2, BRD3, BRD4, and BRDT. It also binds to several other bromodomains which are not included in the BET bromodomain family.
Product Type: Substrate
Shippement Condition: -20°C
