Bcl2L2 Antibody / Bcl-W | V8951-20UG

Bcl2L2 Antibody / Bcl-W | V8951-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: PCRP-BCL2L2-1A4

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF

Buffer: N/A

Limitation: This Bcl-W antibody is available for research use only.

Purity: Protein A/G affinity

Description: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.

Immunogen: Recombinant human full-length BCL2L2/Bcl-W protein was used as the immunogen for the Bcl-W antibody.

Storage: Aliquot the Bcl-W antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.