Description
Bcl2L2 Antibody / Bcl-W (BH3 domain specific) | F54369-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, IHC-P
Buffer: N/A
Limitation: This Bcl-W antibody is available for research use only.
Purity: SAS precipitation
Description: Bcl-w is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.
Immunogen: A portion of amino acids 24-59 from the human protein was used as the immunogen for the Bcl-W antibody.
Storage: Aliquot the Bcl-W antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.