Description
Bcl10 Antibody | RQ4824 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: GDB-2
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This Bcl10 antibody is available for research use only.
Purity: Affinity purified
Description: Bcl10 contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. It is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. Bcl10 is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [RefSeq]
Immunogen: A synthetic peptide specific to human Bcl10 was used as the immunogen for the Bcl10 antibody.
Storage: Store the Bcl10 antibody at -20 °C.
