Description
Bcl-2 Antibody | F47422-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This Bcl-2 antibody is available for research use only.
Purity: Antigen affinity
Description: Bcl-2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). [UniProt]
Immunogen: A portion of amino acids 144-171 from the human protein was used as the immunogen for this Bcl-2 antibody.
Storage: Can be stored at 4oC for one month. For long term, aliquot the Bcl-2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.