Description
Bax Antibody | V7127SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: ARBX-1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P
Buffer: N/A
Limitation: This Bax antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: BCL2 associated X protein/Bax accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. [UniProt]
Immunogen: Recombinant full-length human protein was used as the immunogen for the Bax antibody.
Storage: Store the Bax antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
