Bax Antibody | V7127-100UG

Bax Antibody | V7127-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: ARBX-1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This Bax antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: BCL2 associated X protein/Bax accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. [UniProt]

Immunogen: Recombinant full-length human protein was used as the immunogen for the Bax antibody.

Storage: Store the Bax antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).