Description
BANP Antibody | F53808-0.2ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: 1524CT337.6.32
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, IHC-P
Buffer: N/A
Limitation: This BANP antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Btg3-associated nuclear protein controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).
Immunogen: A human recombinant protein of amino acids 30-390 was used as the immunogen for the BANP antibody.
Storage: Aliquot the BANP antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.