BANP Antibody | F53808-0.05ML

BANP Antibody | F53808-0.05ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: 1524CT337.6.32

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, IHC-P

Buffer: N/A

Limitation: This BANP antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Btg3-associated nuclear protein controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).

Immunogen: A human recombinant protein of amino acids 30-390 was used as the immunogen for the BANP antibody.

Storage: Aliquot the BANP antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.