Description
Bak Antibody | F42652-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IHC, WB, ELISA
Buffer: N/A
Limitation: This Bak antibody is available for research use only.
Purity: Antigen affinity
Description: BAK belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BAK localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Immunogen: A portion of amino acids 56-91 from the human protein was used as the immunogen for this Bak antibody.
Storage: Aliquot the Bak antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
