BACE2 Antibody | F49441-0.08ML

BACE2 Antibody | F49441-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, FACS, ELISA

Buffer: N/A

Limitation: This BACE2 antibody is available for research use only.

Purity: Purified

Description: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by BACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease.

Immunogen: A portion of amino acids 336-365 from the human protein was used as the immunogen for this BACE2 antibody.

Storage: Aliquot the BACE2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.