Description
BACE2 Antibody | F49441-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, FACS, ELISA
Buffer: N/A
Limitation: This BACE2 antibody is available for research use only.
Purity: Purified
Description: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by BACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease.
Immunogen: A portion of amino acids 336-365 from the human protein was used as the immunogen for this BACE2 antibody.
Storage: Aliquot the BACE2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
