Description
BACE1 Antibody | F50758-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, IHC, ELISA
Buffer: N/A
Limitation: This BACE1 antibody is available for research use only.
Purity: Purified
Description: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. [UniProt]
Immunogen: A portion of amino acids 38-70 from the human protein was used as the immunogen for this BACE1 antibody.
Storage: Store at 4oC for up to one month. For long term, aliquot the BACE1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
