B7-H7 (HHLA2)/TCR Activator CHO Cell Line | 78321

B7-H7 (HHLA2)/TCR Activator CHO Cell Line | 78321 | Gentaur US, UK & Europe Disrtribition

Category: Immunotherapy/Cell Line

Application: • Characterize the biological activity of KIR3DL3 or TMIGD2 interactions with B7-H7
• Screen for B7-H7 antibodies

Background: N/A

Description: Recombinant CHO-K1 cells constitutively expressing human B7-H7 (also known as HHLA2: HERV-H LTR-associating protein 2, GenBank accession #NM_007072) and an engineered T cell receptor (TCR) activator. B7-H7 mediates an immune-stimulatory signal via TMIGD2 (Transmembrane and immunoglobulin domain containing 2) in naïve T cells while it delivers an immune-inhibitory signal through KIR3DL3 in activated T cells and Natural Killer (NK) cells.

Product Type: Cell Line

Shippement Condition: -80°C