Description
Autotaxin Antibody / ENPP2 | F54328-0.05ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, FACS
Buffer: N/A
Limitation: This Autotaxin antibody is available for research use only.
Purity: Antigen affinity purified
Description: ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The protein is secreted and further processed to make the biologically active form.
Immunogen: A portion of amino acids 377-406 from the human protein was used as the immunogen for the Autotaxin antibody.
Storage: Aliquot the Autotaxin antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.