Aurora-B Antibody (Aurkb) | F44415-0.08ML

Aurora-B Antibody (Aurkb) | F44415-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, ELISA

Buffer: N/A

Limitation: This Aurkb antibody is available for research use only.

Purity: Antigen affinity

Description: Aurkb may be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity). Phosphorylates 'Ser-10' and 'Ser-28' of histone H3 during mitosis. Required for kinetochore localization of BUB1 and SGOL1 (By similarity).

Immunogen: A portion of amino acids 84-111 from the mouse protein was used as the immunogen for this Aurkb antibody.

Storage: Aliquot the Aurkb antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.