Aurora-A Antibody (Aurka) | F44002-0.08ML

Aurora-A Antibody (Aurka) | F44002-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Mouse

Application: WB, ELISA

Buffer: N/A

Limitation: This Aurka antibody is available for research use only.

Purity: Antigen affinity

Description: Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity (By similarity). Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization.

Immunogen: A portion of amino acids 93-120 from the mouse protein was used as the immunogen for this Aurka antibody.

Storage: Aliquot the Aurka antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.